Wednesday, April 15, 2015

Primobolan - the Cutting Agent For Bodybuilders

Primobolan is a famous drug used in the field of bodybuilding. It is indeed a preferred one as it serves to be a great cutting agent and is one of the rare androgen steroids with mild impact on the beginners and women. An interesting fact regarding this drug is that it is easily available in injectable and oral forms. Primobolan is basically the common name assigned to Methenolone Enanthate. Being an oral and injectable steroid which is mild in nature as compared to other steroids, it is generally taken to be more anabolic steroid in nature and not the androgenic one.

Primobolan’s injectable form is good for the beginners as it does not have any toxic factors for the liver associated with its usage. Also, the drug does not actually convert to estrogen even if taken at high dose and so you can have well cut and ripped body in no time. This is why a lot of bodybuilders prefer taking it over other drugs. More than that, you do not even need to worry about different problems like water retention, development of feminine traits in men and high blood pressure that are otherwise faced with some other steroids.

A number of users claim Primobolan to be free from any side effects except for showing slow results. Indeed the results enjoyed are retain-able and quality muscles. Because of lack of water retention, the gains that you observe with Primo are quality and permanent muscle gains.

The ability to bind with the anabolic receptor makes this steroid a great fat burner. Talking in clinical terms, the steroid helps to reduce breast tumor as well. The drug is further a nice ancillary agent as well. But unlike Masteron, Primo does not aromatize that in turn makes it one of the recommended steroids perfect for muscle gain.

Primobolan is in fact seen more as a cutting anabolic steroid and less of a bulking agent because of it being friendly on male body. With strong binding capacity for androgen receptor, it is pertinent to burning fat. It can thus be used for both- as a cutting and binding agent. But it is better as a cutting steroid because:

    It increases fat oxidation and lipolysis fat burning
    It increases protein synthesis
    It reduces protein breakdown and catabolic hormone
    It offers the users the capability to maintain their muscle mass

So, before you opt for this steroid, have proper information on dosage you need as per your cycle needs. Whether choosing oral or injectable dosage, one point should be remembered at all times that it is nice if you avoid using the drug alone. You need to have effective workout schedule as well to make your bodybuilding goals get fulfilled in no time. You can take medical consultation before using the steroid as the doctor will be in a better position to tell you if using Primobolan can be useful for your health and body or not.

Primobolan is often used in bodybuilding as a cutting agent. Primobolan cycles are meant to improve the effects of bulking agents such as Dianabol or testosterone. Primobolan actually works together with these steroids for enhancing muscle gain. There is no universal rule concerning the best Primobolan cycle because this depends on the individual goals of high blood pressure medication each bodybuilder. For instance, those who only focus on bulking might imagine that there is no reason why they should use any Primobolan cycle. However, they are wrong because there are certain Primobolan cycles which help them improve their muscle mass which would otherwise look flabby and won't have a well defined shape. These cycles are usually done in between primary steroid cycles which promote bulking. Using Primobolan cycles this way is going to ensure both muscle gain and beautifully sculptured muscles. In order to achieve such result a Primobolan cycle needs to be combined with oral steroids that deliver impressive gains. Otherwise Primobolan won't have enough mass to work on. Primobolan cycles which don't also include other steroids aren't usually used, but some might still turn to them for the cutting effect only.

Regardless the Primobolan cycles you decide are best for you, knowing the correct dosage is very important. This is between 300 and 600 mg of intramuscular Primobolan per week and between 100 and 150 mg of oral Primobolan per day. A Primobolan cycle in which this is combined with Deca Durabolin is very popular. It is also a very mild cycle and it consists of 200 mg of Deca Durabolin per week together with the same amount of Primobolan. The dose of Deca Durabolin can be increased up to 400 mg and both substances should be taken through intramuscular injections. Such Primobolan cycles don't produce impressive muscular gains, but these are highly qualitative and easy to maintain on the long run. In other Primobolan cycles, this steroid is used instead of Deca Durabolin or Equipose in cutting purposes. An example of a more advanced Primobolan cycle would consist of combining it with Dianabol, trenbolon and masteron. You need to have 600 mg of Primobolan per week for 14 consecutive weeks. The role of this steroid would be to improve the muscle mass gained because of the other steroids and also to counteract the possible side effects of estrogen.

Tuesday, April 7, 2015

Testosterone Cypionate by Accordo RX

Testosterone is one of the most important hormones any human being will ever produce and it is a hormone all human beings naturally produce, both men and women. While men require nearly ten times the amount of women, in both sexes the hormone plays host to numerous responsibilities in the body that range from muscle tissue growth and preservation, metabolic and sexual function to a host of others all comprising of a well-functioning endocrine system.

Many individuals the world over suffer from low levels of the testosterone hormone, the most common cause being age. As men age their natural testosterone levels decline but this effect can be seen in women as well, especially women who are post-menopause and Testosterone Cypionate is often the means by-which it is remedied. For the individual who suffers from low testosterone he or she may experience a host of problems ranging from muscle and strength loss, a loss of libido and sexual function, increased body-fat, depression, a weakened immune system to a host of other ailments and conditions. In most cases such conditions are easily treated by simply supplementing with a testosterone based hormone and by simply returning levels to a stable yet normal level will in most cases see such conditions resolved.

In a strong sense we can look at TRT therapy in a similar light when examining performance enhancement, the difference simply being taking our testosterone levels beyond the normal range, thereby enhancing the effects of the hormone even more so. For the majority of performance enhancers this will revolve around muscle growth and preservation, increasing strength and overall athletic performance as well as improving metabolic activity within the body.

Testosterone Cypionate use is one of the best methods of achieving such goals as its direct mode of action simply promotes their enhancement. As is caused by the presence of testosterone the hormone dramatically increases nitrogen retention in the muscles as well as overall protein synthesis and further enhances red blood cells by increasing the amount and structural capacity. Testosterone also has the ability to block and reduce glucocorticoid hormones in the body, also known as muscle wasting hormones, the most famous of all being cortisol. These hormones, often referred to as “stress hormones” can have disastrous effects as they destroy muscle tissue and promote fat gain, all leading to slower metabolic activity and making fat-loss more difficult than it needs to be. Further and of particular interest, when the testosterone hormone is present in levels beyond therapeutic measure our natural IGF-1 levels increase and as IGF-1 is a powerful anabolic hormone itself, a hormone that plays a key role within every cell of the body, our total activity in both an anabolic and metabolic nature increases yet again.

Now that you have an understanding of testosterone the obvious point of interest is how does the Cypionate ester play a role and function. The ester of the steroid is largely what determines the steroids half-life and the larger the ester the longer the half-life will be. The ester attached also affects a particular steroids initial activity but and while not of particular great importance it also affects the compounds total mass. The larger the ester the more mass it takes up in the compound; for example, 100mg of testosterone with no ester attached is simply 100mg of testosterone whereas 100mg of testosterone with an ester attached will be a little less than 100mg of actual hormone; how much less will be determined by the size of the ester. In the case of Testosterone Cypionate we have a compound that carries with it a moderately long half-life as Cypionate is a fairly large ester; the half-life of Testosterone Cypionate is approximately 12 days long. As a long ester based anabolic steroid the effects of the compound will not be felt very fast but the total activity will stretch past much further than smaller ester based forms such as Testosterone Propionate.

The Benefits of Testosterone Cypionate:
It should be at this stage fairly easy to see the benefits of Testosterone Cypionate and it doesn’t take a genius to see they are almost everything anyone could ever want out of anabolic steroid use. A common benefit often overlooked is the testosterone hormone’s ability to increase metabolic activity and in-truth this may be one of the greatest benefits of all and for all users of all purposes. For the HRT patient it allows him to garner a healthier physique pure and simple. For the performance enhancer it not only allows him to garner a more pleasing physique but one that is more efficient in nature; the higher our metabolic activity the more efficient our body becomes in most all aspects.

Of course often the principle reason of supplemental testosterone use is to increase mass, strength and athletic performance and Testosterone Cypionate will aid in every aspect and do so remarkably well however, there are important things to understand. If you’re basing your understanding of Testosterone Cypionate on popular culture references regarding anabolic steroids then all you need to do is grab a bottle, fill a syringe, inject and watch the show start; sorry, it doesn’t quite work this way. If you are after a true performance enhancing edge you still have to feed the body properly with adequate amounts of food and physical stimulation, through the use of Testosterone Cypionate we simply enhance these aspects and increase the efficiency. For the TRT patient this might be a relief, for many TRT patients are petrified of testosterone therapy because they assume they’ll turn into the Incredible Hulk; if you do not feed and stimulate properly and in adequate amounts you have nothing to fear, further, HRT doses are typically too low to really do anything in this regard even if you do.

The Side-Effects of Testosterone Cypionate:
When examining the side-effects of Testosterone Cypionate or any testosterone there is some good news right from the start; as testosterone is not a foreign substance it is not a hormone our bodies are unaccustomed to; you’ve been producing it at some level your entire life. Even so, when we enter into our body anything of an exogenous nature there is a potential for negative side-effects and the level of potential can vary with each and every item. The same can be said of all anabolic androgenic steroids, the level of potential varies with each and every one; nevertheless, while there is potential the probability is much lower than with many common over the counter medications, especially when we look at testosterone. Testosterone in many ways shouldn’t really be viewed as a drug, it doesn’t share any traits with what we use to determine if something is a drug and it’s not, it’s a hormone and there is a big, big difference.

Regardless of your purpose be it performance enhancement, TRT or a full blown HRT program you will be very hard pressed to find a better testosterone than Testosterone Cypionate. In the world of TRT most will find 200mg every 7-10 days to be fairly common place and generally speaking about as high as you’ll ever go but of course in performance enhancing doses will necessarily be much higher. For the performance enhancer minimal dosing will generally be in the 400mg-500mg per week range and most commonly split into two even doses twice per week; for example, for 400mg total per week you might administer the hormone at 200mg on Monday and 200mg on Thursday continuing such a schedule until your total duration is complete.

For many 500mg per week will be as high as they ever need to go but in more hardcore circles it is not uncommon for doses to reach levels of 1,000mg per week and at extreme elite levels, especially in competitive bodybuilding they can go much higher. Keep in mind, while the benefits of use will increase as the dose does so will the potential and probability of adverse effects. There is a strong risk to reward ratio at play and in the end you are the only one who can determine how far you want to go with that. Yes, absolutely anabolic steroids and especially those of a pure testosterone nature such as Testosterone Cypionate can be used safely and effectively but responsible use will always prove to be the ultimate key.

Thursday, March 26, 2015

GP Clomiphene by Geneza Pharmaceuticals

Clomid (Clomiphene Citrate) belongs to a category and class of drugs known as selective Estrogen receptor modulators (SERMs). Selective Estrogen receptor modulators belong to an even broader class of drugs known as anti-estrogens. The other subcategory of drug under the anti-estrogens category is known as aromatase inhibitors (AIs), such as Aromasin (Exemestane) and Arimidex (Anastrozole). Aromatase inhibitors differ greatly from SERMs in their action and how they deal with the issues of estrogen control. The misunderstanding that SERMs, such as Nolvadex and Clomid (GP Clomiphene), serve to lower estrogen levels must first be addressed before delving into any further details.

If you are looking for a highly effective and safe antiestrogen to reduce or prevent estrogenic side effects immediately before the end or at the end of an anabolic steroid cycle, Clomid (GP Clomiphene), also known as Clomiphene citrate, would be a good choice.

This SERM (selective estrogen receptor modulator) is medically recommended to women with an inability to conceive on their own. GP Clomiphene is also admired for reducing or inhibiting the formation of excess estrogens in the body, especially after an anabolic steroid cycle involving harsh or aromatizable steroids, and restoring the natural production of hormones such as testosterone, besides revitalizing the levels of luteinizing hormone and follicle stimulating hormone.
Clomid (GP Clomiphene) use is also associated with enhanced bioavailability of anabolic steroids and performance enhancing drugs that are part of a bulking steroid cycle or cutting steroid cycle.

It is also used for treating polycystic ovarian syndrome (PCOS) related infertility or cases of unexplained infertility or when expensive and invasive fertility treatments, like IVF are not preferred by couples. Pregnancy-keen women can have sex for pregnancy one to two days before ovulation or seek medical advice for help in predicting the most fertile days. By stimulating an increase in the levels of hormones that help the growth and release of a mature egg (ovulation), Clomid aid conception and boost fertility. The incidence of multiple pregnancy (including twins, triplets, quadruplets, and quintuplets) can be greater when conception occurs during a cycle in which GP Clomiphene therapy is taken.

Oral Clomid (GP Clomiphene) may be recommended by medical practitioners for treating an insufficiency in ovulation, hypothalamic pituitary gonadal axis function test, low sperm count, male infertility, and study of the function of the ovaries.

The substance name of Clomid (GP Clomiphene) is 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy] triethylamine citrate (1:1) and its molecular formula of C32H36ClNO8 (citrate) or C26H28ClNO. The antiestrogen has a half-life of 5-7 days, Clomid tablets include Clomiphene citrate USP as the active ingredient, and the list of inactive ingredients includes magnesium stearate, pregelatinized cornstarch, lactose and cornstarch. It has the molecular weight of 598.09 g/mol at the base and it is a variety of geometrical isomers [cis (zuclomiphene) and trans (enclomiphene)] such as of abut 30-50 % of the cis-isomer.

In the world of professional sports dominated by use of steroids and performance improving drugs, Clomid (GP Clomiphene) is used by sportsmen for coming off their steroid cycles, safely and effectively. By reducing harmful effects caused by intense workouts on the muscles, Clomid (GP Clomiphene) helps sportsmen in limitless ways. The antiestrogen is also admired for its unique potential to reduce estrogenic side effects such as oily skin, acne, gynecomastia, and bloating besides restoring production of natural testosterone in as short as three to five weeks.

Clomid (GP Clomiphene) use is also related to dramatic improvements in terms of HPTA (hypothalamus-pituitary-gonadal axis) by promoting the stimulation of more gonadotropin discharge from the pituitary to increase Luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This gives a signal to the testes to produce more of testosterone, which proves extremely beneficial at the end of steroid cycles where production of testosterone, the primary male sex hormone, may get hampered due to use of some drugs. Clomid (GP Clomiphene) use can even enhance the count and fertility of male sperm to some extent.

The ideal dose of Clomid (GP Clomiphene) is 50 mg per day for a period of five weeks or as per medical advice. Clomid (GP Clomiphene) doses can be increased after medical evaluation and recommendation in case of women who do not ovulate in response to cyclic 50 mg Clomid dose. The maximum dose of Clomid is 100 mg daily for 5 days and the drug should not be used for more than three treatment cycles. Sportsmen can take the antiestrogen for a period of three or five weeks. It may be used 3 weeks after using Deca Durabolin, 3 weeks after using Sustanon 250, 2 weeks after using testosterone enanthate, 3 weeks after Trenbolone, 17-21 weeks after using Equipoise, 4-8 weeks after using Dianabol, 8-12 weeks after using Winstrol, and 3 weeks after using testosterone propionate.

Use of Clomid (GP Clomiphene) is not recommended to pregnant or lactating women or women who may become pregnant while taking Clomid. It is also not recommended to children or those suffering from high blood pressure, stroke, kidney damage, liver damage, prostate cancer, breast cancer, or testicular cancer. Clomid is also not recommended to those having allergy to Clomid or any of its ingredients.

Clomid (GP Clomiphene) use is not recommended to those who have a hormone-dependent tumor, experiencing abnormal vaginal bleeding of unknown cause, suffering from fibroid tumors of the uterus, have ovarian cysts (not associated with polycystic ovary), have liver disease or have had reduced liver function in the past, or suffering from thrombophlebitis (inflammation of a vein with formation of a blood clot).

Use of GP Clomiphene should not be made by individuals suffering from high blood fats (cholesterol), bone problems (such as osteopenia, osteoporosis), stroke or blood clots, heart disease (such as chest pain, heart attack, heart failure), high blood pressure, kidney problems, and liver problems.

Friday, March 20, 2015

Strong anabolic compound Dianabol

Dianabol is methylated at carbon 17-alpha on its structure (this is simply the addition of a methyl group at the 17th carbon). This process, known as C17-Alpha Alkylation, allows the anabolic steroid to be administered orally and still have a measurably strong effect on the body. Without this modification, it is impossible for any anabolic steroid to survive liver metabolism in significant enough quantities to promote any measurable effects in the body – the result is that extremely miniscule amounts of the anabolic steroid reaches the bloodstream to perform its job.

It also possesses a double-bond between carbons 1 and 2. This modification in particular is what grants it a ‘milder’ androgenic strength in comparison to its parent hormone Testosterone. This double-bond is what limits Dianabol’s affinity to bind to the androgen receptor in different tissues in comparison to Testosterone. It is these modifications that also allow Dianabol’s half-life to exceed that of Testosterone (Dianabol’s half-life is 4.5 – 6 hours). An additional benefit of these chemical modifications is Dianabol’s lower affinity for binding proteins to bind to it, such as Sex Hormone Binding Globulin (SHBG). These binding globulins (in this case SHBG), which are proteins, bind to sex hormones such as Testosterone, Estrogen, Dianabol, etc. and render them inactive temporarily. What results is essentially a bound hormone that floats around in the bloodstream and does nothing – it cannot bind to receptors or do anything – and is essentially useless. These are the chemical features are that grant it its status of being a significantly potent anabolic steroid. One interesting point to note, however, is that it possesses a weaker interaction with the androgen receptor in comparison to Testosterone and many other anabolic steroids, yet it is a very strong and potent hormone in comparison. It is therefore speculated that much of Dianabol’s activity is that of non-receptor mediated activity. With this being said, Dianabol’s anabolic rating is known to be a rating of 210 in contrast with Testosterone’s anabolic rating of 100. What can be seen here is it possesses slightly over double the anabolic strength of Testosterone, and this is because of the described structural modifications it possesses.

Dianabol does succumb to some limitations of its own, with the first being its C17-Alpha Alkylated property. As previously mentioned, C17-Alpha Alkylation allows an anabolic steroid to become orally active and bioavailable – without it, the anabolic steroid would not survive liver metabolism. However, the negative downside in this case is that of increased hepatotoxicity (increased liver toxicity). C17-Alpha Alkylation allows an anabolic steroid to become more resistant to hepatic breakdown, and any compound that is further resistant to hepatic breakdown with always have greater hepatotoxicity associated with it. As a result, it is a smart choice to run this oral for periods no greater than 4-6 weeks at any given time in a cycle. This is to ensure healthy liver function, and for proper liver recovery following the cycle. It is because of the risk of hepatotoxicity that Dianabol’s main function in a cycle is to serve as a supportive kickstarting compound. Dbol, nor any oral anabolic steroid, should ever be run solitarily on its own. Testosterone in some form no lower than a TRT (Testosterone Replacement Therapy) dose should always be run with an oral anabolic steroid.
From being the first ever steroid produced by man to the most popular steroid of today’s time, Dianabol has come a long way.  Usually people tend to take up new steroids that visit the market over older ones but D-bol has a unique history of have a loyal following of users from the time it was first manufactured.

From being the first ever steroid produced by man to the most popular steroid of today’s time, Dianabol has come a long way.  Usually people tend to take up new steroids that visit the market over older ones but D-bol has a unique history of have a loyal following of users from the time it was first manufactured.

The major function of Dianabol is development of quality muscle mass as well as strength gain. Since these two are prime objectives of people seeking steroid use, D-bol seems to be the best option to be used in the bulking phase of the cycle. The reason D-bol is preferred over other drugs is because it renders many other added benefits to its user and also keeps them away from the risk of side effects. The strength and muscle gain in case of Dianabol is mainly due to the compound methandrostenolone, which is the most active ingredient of this drug. Its main users are bodybuilders, power lifters and athletes preparing for competition purposes.

However, good news about this steroid is that it also produces many added benefits in its users. To start with, it enhances the person’s ability to train for longer hours without getting tired soon. It does it by boosting the process of protein synthesis in the tissues which in turn increases the level of nitrogen in the body. This increase in nitrogen enhances the person’s capacity to endure more exertion. Dianabol also increases the level of body insulin in the blood as a result of which the person feels more relaxed and light. It is known to improve appetite and sleep as well.

PROVIRON    100 tab

DIANABOL    230 tabs

CLOMID         15 tabs

One of the most important benefits of D-bol comes after the steroid cycle is over. It establishes what is known as a temporary anabolic state in the body which does not allow proteins present in the tissues to breakdown into amino acids. This helps keep the muscles firm even when the person has stopped working out in the post cycle phase.

    ANADROL     60 tabs
    NOLVADEX   25 tabs
    SUSTANON   4250 mg or 17 amps/1 ml/250 mg
    DIANABOL    110 tabs
    DECADURABOLIN   3000 mg or 15 amps/2 ml/ 200 mg
    HCG 5000 IU  x 1
    CLOMID         25 tabs

It must be noted that Dianabol is a strong anabolic compound and should not be administered in the body for a very long period of time. This is because its excessive use might cause certain conditions like high blood pressure and toxicity of liver to appear. In extreme cases, one might confront estrogenic effects like water retention and gynecomastia.

A 4-week break after the completion of this steroid cycle is a must. For faster recovery and maintenance of the muscle tissue gained, intake of Clenbuterol during this phase is highly recommended.

D-bol happens to be one of the most popular steroids today and so can be easily bought from any reputed online steroid store or a pharmacy. The good news is that it can be bought with as well as without a prescription.

Thursday, March 12, 2015

Benefits of Stanozolol drug

Stanozolol, most commonly known as Winstrol or Winny is a powerful anabolic steroid that can be found in both oral and injectable forms, the injectable form being commonly known as Winstrol Depot. While there are other steroids that can be found in both injectable and oral forms Stanozolol is one of the few that works equally well in either form further, the injectable Winstrol Depot can be taken orally just as the standard oral tablet form. By its ease and convenience of administration, coupled with more hype surrounding the steroid than any other form Stanozolol remains one of the most popular steroids of all time.

All medications, steroidal and non-steroidal alike carry with them possible negative and adverse side-effects, in that GP Stan makes no exception. It is important to note, such side-effects are by no means guaranteed and when speaking of anabolic steroids such effects are often largely avoidable through responsible use. Many anabolic steroids can have a negative effect on one’s cholesterol and often this problem is avoidable by proper diet and even through aromatase inhibitor use as cholesterol issues are often estrogenic related. However, Stanozolol has a very pronounced negative effect on cholesterol and for this reason use must necessarily be kept brief and in responsible levels.

Stanozolol can also increase liver enzymes quite heavily, especially when taken in tablet form, as oral Stanozolol is a 17-aa steroid. However, most will find their liver values return to normal after use is discontinued and the liver will not be harmed. Even still, responsible use must be implored but understand, even massive doses of Stanozolol are not as damaging to the liver as every day alcohol consumption.

While GP Stan is a strong anabolic with a low androgenic nature it is far from the most powerful anabolic available but far from the weakest as well. Without question the attributes of this anabolic steroid are best seen during a cutting cycle as Stanozolol will provide a harder more vascular look to an already lean physique. However, the benefits do not end with hardening, GP Stan by its nature is well-suited for increasing strength, even when dieting which can normally be very difficult, no, one will not gain massive strength when dieting but it can go up a little, especially in the early stages. By its strength attributes Stanozolol remains a favorite for many athletes in a host of various performance sports.

While an excellent steroid to use when dieting GP Stan will not do a lot for you when trying to bulk up in-terms of actual growth. It can have a place in a bulking cycle for secondary purposes but most will stick with powerful steroids with strong androgenic qualities for this purpose. Nevertheless, whenever the steroid is used it is important to note it will suppress natural testosterone production to a degree and most men will necessarily supplement with some form of exogenous testosterone. While it will suppress natural production it will not do so to the extent of many other steroids but still enough to warrant caution and remedy.

As both injectable and oral forms will produce the same results, administration in-terms of frequency will follow suit and be identical regardless of the form at hand. As injections can be very painful with this steroid due to the Depot version being suspended in water many choose to simply drink it or take oral tabs; regardless of the form every day administration will prove to be optimal. However, every other day administration will yield positive results as the half-life extends to 24 hours but most will find every day administration to be the most efficient.

To get the most bang for your buck most men will find 50mg of Stanozolol to be just about perfect with 100mg being about as high as you’d ever want to go. 100mg per day is very common in competitive bodybuilding circles but generally only the last 7-10 days before the competition as that high of a dose for long periods can be very side-effect ridden. In most cases, 50mg per day for approximately 6-8 weeks will prove to be fantastic.

For our female athletes, 5mg-10mg is perfect and most are highly cautioned against going above this dose and staying within the 6-8 weeks of total use. Failure to abide will result in nasty virilization effects, even though it is only slightly androgenic it’s still androgenic in nature. When used responsibly most women will find Stanozolol to be very well-tolerated.

Tuesday, March 3, 2015

The Benefits of GP Test Prop (Testosterone Propionate)

Anabolic steroids are synthetic versions of testosterone, the body’s natural sex hormone. They assist athletes by facilitating efforts to gain strength and muscle mass for increased muscular endurance, power and speed.

Male hormones such as testosterone and its metabolite dihydrotestosterone are responsible for the developmental changes that occur within the male body through adolescence. Steroids possess both androgenic and anabolic properties. Some of the androgenic effects include changes in sexual characteristics such as shrinking of the testicles, hair growth on the body and face, hair loss on the scalp, and increased aggressiveness. Athletes are primarily concerned with the anabolic characteristics of steroids including accelerated development of the muscles, connective tissues, bones, and red blood cells.

The benefits of Testosterone Propionate are truly great and in short the benefits most anyone would desire to hold if anabolic steroids were being used. Through the use of Testosterone Propionate we aptly create a playing field perfect for almost any situation be it bulking, cutting or simply trying to provide an added athletic edge. Through its use the individual can expect to see increases in lean tissue and strength, decreased body fat due to improved metabolic function as well as a greater ability for healing and recovery.

A common misconception is that Testosterone Propionate (GP Test Prop) is only well-suited during a cutting cycle and while it is definitely perfect for a cutting cycle it is perfect because it is testosterone, not because it has the Propionate ester attached. The truth is simple, any testosterone form can be used in a cutting cycle or bulking cycle with equal effectiveness, however, there are variances to consider. As a short ester steroid Testosterone Propionate (GP Test Prop) must be necessarily administered at a minimum of every three days with every other day being far more optimal; because many will be using other short ester steroids during a cutting cycle often it makes sense to use Testosterone Propionate (GP Test Prop) during this time and simply administer them all at once. However, because peak levels are so easy to control with the use of Testosterone Propionate (GP Test Prop) due to the short ester being attached many, especially in the competitive bodybuilding world use Testosterone Propionate (GP Test Prop) in their off-season as well.

Testosterone Propionate (GP Test Prop) like all forms of testosterone is highly anabolic and androgenic, equal in both rights. As by its nature it is simply a synthetic version of the testosterone hormone naturally produced in the human body by both men and women and essential to a properly functioning endocrine system. While inadequate levels, particularly low levels are generally not life threatening they can be quite bothersome and can lead to more serious problems when not dealt with appropriately. To give you an idea of the importance of the hormone we only need look at the effects of low levels; those who suffer from low testosterone find a body transformation in the opposite desired direction to be very common place; increased body-fat, decreased muscle tissue and strength can all occur and be very difficult to deal with and in many cases impossible when levels are too low. Further, because testosterone is responsible in part for sexual function many men find they experience a decrease in libido, erectile dysfunction when levels are too low, as well as lack of mental focus, energy and even the onset of depression. While these are not life threatening conditions on their own, as you can easily see some of them are pretty serious and there isn’t one any man would wish to have bestowed on him. Conversely, when we look at the effects of low testosterone we can easily see how increased levels would have the opposite effect; take each condition previously listed and take it in the opposite direction towards improvement, which is exactly why testosterone is known as a performance enhancer.

By its very nature Testosterone Propionate (GP Test Prop) dramatically increases nitrogen retention in the muscle allowing protein to be stored in the muscle to a larger degree; as protein is the building block of muscle and increased lean tissue improves our metabolic rate, on this basis alone we have a highly desirable hormone; however, the good news does not end there. As by its mode of action testosterone has the ability to block and reduce muscle wasting hormones known as glucocortico steroid, most commonly cortisol. While testosterone truly has seemingly limitless properties, as it pertains to performance, of particular interest is its ability to greatly increase IGF 1 production in the body; as you understand IGF 1 is a very powerful peptide hormone of a highly anabolic nature and plays a key role alongside human growth hormone, another potent peptide based hormone.

Testosterone Propionate (GP Test Prop) was one of the first anabolic androgenic steroids ever synthesized and made ready for human use in mass production and as such is one of the most popular anabolic steroids of all time. While there are hundreds of anabolic steroids and forms within each, Testosterone Propionate (GP Test Prop)  is largely one of the easiest to understand as it is very basic in composition and simply a pure testosterone. However, as simple as it is it further remains very powerful and highly effective yet many understand Testosterone Propionate (GP Test Prop) as well as they understand the most basic algorithms used in space exploration.

Testosterone Propionate (GP Test Prop) is one of the more popular testosterone forms used the world over and one of the more popular anabolic androgenic steroids of all time. As testosterone was the first anabolic steroid every synthesized Testosterone Propionate was the first form to hit the shelves in mass quantities made ready for human use. Like the popular oral steroid Dianabol, Testosterone Propionate has been available for a very long time and like Dianabol it is just as popular today as its ever been. One of the reasons Testosterone Propionate (GP Test Prop) holds such high popularity is simply because it is pure testosterone, a very versatile anabolic hormone; further, most who use it find it very easy to control; while all testosterone forms are comprised of the same identical active hormone because the Propionate version is so fast acting and short lived due to its very nature it is perhaps the most controllable testosterone available with stability and peak levels being very easy to maximize and held in an efficient manner.

Thursday, February 26, 2015

The Importance of Testosterone In the Body and its Functions

As the principal male sex hormone, Testosterone is responsible for governing the development and maintenance of male secondary sex characteristics (deepening of the voice, bodily and facial hair growth, increased sebum secretion on the skin, and development and growth of the male sexual organs which includes spermatogenesis (development of sperm) and increase in libido and sexual function. All of these functions are known as male secondary sex characteristics as well as androgenic (masculinizing) effects and they cannot function or develop properly or efficiently in an environment in which Testosterone levels are inadequate.

Although it is considered an androgenic effect as well, the muscle growth promoting effects have been categorized more independently as an anabolic effect.
The word ‘anabolic’ refers to the promotion of tissue growth within the body, and in this case refers to the growth promotion of muscle tissue. This occurs through Testosterone’s ability to signal an increase in the rate of protein synthesis (the rate at which the body can synthesize and create new strands of contractile protein within muscle tissue). Hence this is why males on average naturally are more muscular than females and why males normally carry a heavier lean body weight than females do. Females possess very miniscule amounts of Testosterone, and this can be seen where it has been discovered that the average male endogenously produces approximately 2.5 – 11mg daily of Testosterone. In comparison, females manufacture approximately 0.25mg daily of Testosterone, which is approximately 90% less (or 1/10th) than men. In females, their primary sex hormone is Estrogen, and it too is a steroid hormone, although not an anabolic steroid. By virtue of this distinction, Estrogen exhibits very different effects in the body compared to Testosterone, hence the vast differences between males and females. For example, women naturally possess a ‘softer’ tone and naturally hole more body fat than males do, which is a typical characteristic of Estrogen as it does promote fat retention/storage in various key areas of the body, which is important for female-specific roles (such as pregnancy and fetal development). In addition to this difference, females also exhibit a shorter height, vastly less muscle mass than men, and are far more prone to age-related bone deterioration. This is a direct result of the difference in hormonal dynamics between men and women.

How Testosterone Specifically Works at the Cellular Level:
As with all hormones, the systemic and cellular effects of Testosterone are quite intricate and involve various mechanisms that are both direct as well as indirect in its effects. All anabolic steroids share this property, as essentially, all anabolic steroids are derivatives of Testosterone and therefore possess much of the same properties just as a son shares the same genetic properties passed down from the parent. There are many tissues in which Testosterone exhibits its effects. Of course, the beginnings of the journey in Testosterone’s job involve its transport systemically in the bloodstream as it is pumped throughout the body. Through this avenue of travel and transport, the hormone is free to travel to a variety of target tissues within the body and act as a messenger to tell those cells within those tissues what to do. The specific target tissues of Testosterone include muscle tissue (skeletal muscle), sub-dermal and dermal tissue (beneath the skin and the skin respectively), the scalp, kidneys, bone, the central nervous system, and prostate. What occurs in these tissues is the same general action and activity of all hormones: the hormone binds to a receptor situated either on or within the cell of the particular tissue type, and will initiate a message to the cell to instruct the cell to perform a particular job. In the case of steroid hormones, such as Testosterone and Estrogen, the specific receptors are located inside the cell. Testosterone will specifically bind to androgen receptors there in order to initiate its effects. Only steroid hormones possess the ability to bind to receptors located within cells, as the steroidal nature of Testosterone, Estrogen, Cortisol, or any other type of steroid hormone allows the hormone to be of a fat-soluble nature.

Other hormone types such as peptide hormones (also known as protein hormones) must bind to receptors located on the outer surface of the cell membrane, as they cannot proceed inside the cell to interact with receptors there. Testosterone can therefore only affect tissues and cells in the body that retain the specific hormone receptor required (the androgen receptor) and therefore will only affect certain tissues and cells in the body. All hormones of all 3 types (steroid hormones, peptide hormones, mono-amine hormones) operate in this hormone-receptor interaction and this is what they all do. Although it is a very vague and non-specific description, the interaction with a hormone binding to a receptor site is described within science and biology as being very much like a lock and key, in which the key is the hormone and the lock is the receptor – both need to fit almost perfectly with one another for a specific action to occur.

Non-steroid hormones, such as peptide and mono-amine hormones operate in the same lock and key manner, but they (as previously mentioned) will bind to and activate receptors located on the outer surface of the cell. The manner by which non-steroid hormones transmit signals through receptors is different from steroid hormones, whereby a peptide or mono-amine hormone will bind to the receptor  located on the surface of the cell, and this will enable various enzymes and proteins within the cell to act as messengers. These proteins that are then activated as messengers are known as ATP (Adenosine Triphosphate) and cAMP (cyclic AMP), which then travel within the cell to the nucleus of the cell in order to activate gene transcription. Although the general function of non-steroid hormones are the same as steroid hormones, the actual steps and specific action in certain stages is indeed different.

As previously mentioned, Testosterone will enter the target cell(s) by diffusion through the cellular phospholipid bilayer (the layer that encases and encompasses the whole cell), and it will travel through the cytosol (the fluid-filled space inside of the cell) towards the androgen receptor. Once the receptor is located, Testosterone will then bind with the receptor to form what is properly known as the receptor complex. The complex (or ‘receptor complex’) refers to the now bound receptor and hormone together as one. When this occurs, the complex then travels to the nucleus of the cell, which is where it will activate certain DNA sequences. These specific DNA strands/sequences are specific to the intention of Testosterone’s effects on the cell, and they are known as the ‘hormone response element’. For example, in the case of muscle cells, this will activate gene transcription (copying and reading of that specific code of DNA) that will instruct the cell to begin the synthesis and construction of contractile proteins that will ultimately increase muscle strength and muscle size. In layman’s terms, Testosterone is responsible for going into a cell, unlocking the container inside the cell that contains the instructions/blueprints for the cell to do a specific job, and it then tells the cell to do this specific job. In the example given with muscle cells, it informs the muscle cell to begin growth of new muscle tissue.

Thursday, February 19, 2015

The benefits and capabilities of GP Mast cycles

GP Mast  (Drostanolone Propionate) is a dihydrotestosterone (DHT) derived anabolic steroid.  Specifically, GP Mast is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position, This protects the hormone from the metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle. It also greatly increases the hormone’s anabolic nature. This simple structural change is all it takes to create Drostanolone, and from here the small/short Propionate ester is attached in order to control the hormone’s release time. Drostanolone Enanthate can also be found through some underground labs, which does not have to be injected as frequently, but it is somewhat rare compared to the Propionate version. On a functional basis, GP Mast is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer.
In fact, the combination of Masteron (GP Mast) and Nolvadex (Tamoxifen Citrate) has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders as it could actually prohibit the need for an anti-estrogen when used in the right cycle. This will also prove advantageous during the cutting phase due to the hardening effects it can provide. Masteron carries relatively low anabolic and androgenic ratings; however, these ratings are somewhat misleading. It’s important to remember DHT, the basis of Masteron, is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor. This again promotes a harder look and can also enhance fat loss. Most all anabolic steroids are well-noted for enhancing the metabolic rate, but strong androgen's have a tendency to directly promote lipolysis. As an anabolic, GP Mast isn’t well-known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass.

Effects of Masteron:
Without question, the effects of GP Mast will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean. This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Masteron will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti-estrogenic effect will simply enhance this overall look. For those that are not competitive bodybuilder lean, it is possible that the effects of Masteron may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced. As a potent androgen, GP Mast can benefit the athlete looking for a boost in strength. This can be a very beneficial steroid for an athlete who is following a calorie restricted diet in an effort to maintain a specific body weight necessary for his pursuit. The individual could easily enjoy moderate increases in strength and a slight improvement in recovery and muscular endurance without unwanted body weight gain. As a bulking agent, the effects of GP Mast n will prove to be rather week. It is possible the hormone could provide gains in mass similar to Primobolan Depot, which won’t be that strong either, if the total dose was high enough. However, the relative gain in size will be very moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. There are those who may wish to include GP Mast in a bulking plan for its anti-estrogenic and fat loss effects. The latter would ensure they kept their body fat gain minimized during off-season bulking phases, but this isn’t reason enough to use it in this phase. Body fat should be controllable without it. As for the anti-estrogenic effects, off-season cycles are normally comprised of large amounts of aromatase activity due to high doses of testosterone. Progesterone activity is also commonly high with the addition of Nandrolone compounds and possible Trenbolone. Consider additional Anadrol or Dianabol and this estrogenic activity can become very pronounced. Unfortunately, while possessing anti-estrogenic effects, Masteron will not be strong enough to combat this level of estrogenic activity.

GP Mast (Masteron) accomplishes for the user is its synergistic effects with the use of other anabolic steroids in Masteron cycles. GP Mast is indeed a stronger anabolic than Testosterone itself, but it does not possess an anabolic rating very significantly above Testosterone itself, and might be weaker in some instances. Masteron therefore makes up for its lack of anabolic strength in its ability to enhance the effects and capabilities of other anabolic steroids it may be stacked with within a Masteron cycle. Very rarely is Masteron ever utilized on its own, and so its greatest capabilities and benefits arise with the use of other anabolic steroids alongside it. Masteron’s anti-estrogen capabilities through its aromatase inhibition does indeed contribute to this, but it also has the capability of binding to SHBG (Sex Hormone Binding Globulin), preventing that SHBG from binding to the other anabolic steroids being used, such as Testosterone. SHBG is a protein that binds to sex steroids, such as Testosterone, and renders them inactive for as long as SHBG is bound to them (this is the difference between ‘free’ Testosterone and ‘bound’ Testosterone, where bound Testosterone has been bound to SHBG). Many DHT-derivatives exhibit this beneficial and synergistic effect, and Masteron shares this benefit as well.

The benefits and capabilities of GP Mast cycles are best taken advantage of with the use of other anabolic steroids alongside Masteron itself. Although Masteron is not ideal for the purpose of bulking, its use in bulking cycles can be validated through its use alongside Testosterone in a bulking cycle, for example. Run on its own, Masteron is regarded as a sub-optimal anabolic steroid. It still reserves its special place as a precontest and/or cutting compound that is best used alongside other anabolic steroids.

Beginner Masteron cycles would typically utilize some form of basic Testosterone (Enanthate, Cypionate, or most commonly, Propionate) at a general dose of 400 – 500mg weekly, alongside a Masteron dosage of around 400mg per week. This would generally be a cutting or pre-contest cycle in which the user’s goal is to shed body fat and to ‘harden up’ the physique. The reason for the common use of Testosterone Propionate in Masteron cycles is primarily due to the fact that Masteron is readily and primarily available as Drostanolone Propionate and it therefore melds perfectly with Testosterone Propionate for obvious reasons.

Intermediate Masteron cycles will usually introduce a third compound into the Masteron cycle, usually an oral anabolic steroid. Winstrol or Anavar (or even Primobolan) are typical choices. Once again, such a cycle would be a precontest or fat loss cycle, which is the reason for the inclusion of such compounds as Winstrol, Anavar or Primobolan, due to the fact that they are all known as being non-estrogenic compounds typically utilized for the purpose of lean mass or cutting body fat. An oral steroid typically used for bulking, such as Dianabol or Anadrol, are rarely combined with Masteron. However, the truth is that these compounds can also be thrown into Masteron cycles as well, but this is a fairly rare occurrence considering the nature of Masteron itself.

Due to the effects of Masteron on estrogen related side effects, Masteron is a very useful tool (especially in competitive bodybuilding) when cutting. As higher levels of estrogen result in water retention, Masteron inhibits water retention, and many users claim that their muscles feel very full and tight on Masteron, with it giving them amazing 'muscle pumps' in the gym. Use of Masteron (in combination with other appropriate meds) at low body fat levels results in the user seeing fine detail of the muscles being accentuated, such as striations and the fine details of the muscle. Masteron helps draw out the water from between the skin and the muscle giving this very cut look (at low body fat levels). Not many other AS medicines can give such effects on muscle detail as those seen with Masteron.

Despite these effects of Masteron, it is a rather weak AS in itself. One would hardly benefit at all from use of Masteron on its own, and furthermore use of Masteron alone may result in loss of libido due to shutdown of the body's natural testosterone production. For these reasons, it is always recommended to stack GP Mast  (Masteron) with other steroids.

The dosages that should be used with Masteron are:

    350-500mg per week (propionate version, injected every other day)
    400-600mg per week (enanthate version, injected twice per week)

An example of an excellent cutting cycle for an advanced user would be: (6-10 weeks)

    150mg Testosterone propionate every other day
    50mg Trenbolone acetate every day (or 100mg every other day)
    150mg Masteron (propionate) every other day
    50mg Winstrol every day, last 4 weeks of cycle only

Of course with such an intermediate/advanced cycle, the user could also incorporate other medicines such as Clenbuterol, Ephedrine, T3, growth hormone, IGF, etc.

A more novice cutting cycle may consist of: (6-8 weeks)

    100mg Testosterone propionate every other day
    100mg Masteron (propionate) every other day

When abused or overdosed, GP Mast  (Masteron) can lead to oily skin, acne, body/facial hair growth, deepening of the voice, and hair loss. It may even cause increased sebum secretion (oily skin), increased bouts of acne (associated with increased sebum secretion), bodily and facial hair growth, and the increased risk of male pattern baldness. In women, Masteron can cause side effects like development of male secondary sex characteristics such as deepening of the voice, growth of body and facial hair), clitoral enlargement, and menstrual irregularities. Abuse of this steroid can even lead to suppression of the HPTA (Hypothalamic Pituitary Testicular Axis) and natural endogenous Testosterone production. Therefore, the use of post cycle therapy drugs like Clomid or Nolvadex is highly recommended to restore the normalization of the HPTA and endogenous Testosterone production as quickly as possible.

Thursday, February 12, 2015

Trenbolone very powerful steroid by Geneza Pharmaceuticals

Trenbolone is a very powerful steroid that has never been FDA approved for use in humans. It was originally developed as Finaplex pellets for use as a veterinary product to be put under the skin of cattle. However over time bodybuilders have realized its unique properties and powerful benefits and it has become a favorite anabolic steroid for many, despite having more harsh side effects than most other steroids. Many people would convert the pellets into an injectable form, in a rather crude and dangerous manner that would neither be safe nor sterile, and poses many risks. For the user who understandably likes to stick to pharmaceutical grade steroids, unfortunately there is no such form of trenbolone available.

Trenbolone is a highly androgenic steroid, with binding to the Androgen Receptor (AR) in the region of three times as high as testosterone. It does not aromatise and so is not subject to estrogen side effects. In addition to high androgenicity, it is also extremely anabolic too, thus is very good at building muscle mass, and retaining muscle mass in a calorie deficient mode. It is also thought that Trenbolone inhibits cortisol production directly through the glucocorticoid receptors.
Trenbolone is often found to be a body transforming drug, and also can aid a little in fat loss. This may be due to the very strong binding of trenbolone to the AR, which has been postulated to be one mechanism that results in the activation of fat loss pathways, possible through direct binding to fat cells' ARs. This makes Trenbolone a favourite among bodybuilders for cutting, and in addition to these benefits, Trenbolone usually results in large increases in strength due to its high androgenic effects.

Typically today underground labs produce Trenbolone acetate as 75g/ml or 100mg/ml. It is often recommended first-time users of Trenbolone to use the faster acting acetate in case the side effects become too much for the user, they can then come off of the steroid very quickly and it is out of the system much quicker than, for example, the Enanthate ester. For the novice user, 75mg or 100mg every other day (eod) is advised, however due to the acetate ester being even shorter than a Propionate ester and the half life 1 day or less, to both reduce sides and aid gains, it is advisable that the user (if they can bear every day injections) injects Trenbolone acetate every day (ed), at 37.5-50mg ed.

More advanced users may find that taking the Trenbolone to amounts over 500mg per week has very desirable effects on strength and body composition, however note that the side effects will also increase with the increase in dose. Due to the negative effect that Trenbolone has on libido, it is not generally recommended to take Trenbolone without testosterone. However, one can take Trenbolone for short periods without testosterone and introduce an aid such as Proviron (metsterolone) to help with the libido issues, along with proper extensive post cycle therapy (PCT) for recovery. A typical test-free cycle with trenbolone may include something like 600mg Primobolan per week, 400mg trenbolone enanthate per week, for 10 weeks, PCT starting 2 weeks after last injections.

Side effects of Trenbolone are very different. Trenbolone is the one that should be used with extreme caution and only after plenty of research into its side effects and common cycles have been carried out. Trenbolone side effects can be very bad to many users, so much so that they will not use it despite its very positive effects on the body and strength. Firstly, as Trenbolone is so androgenic, all side effects that are seen with strong androgen's can be expected (if prone) with Trenbolone. If one is prone to male pattern baldness (MPB) than Trenbolone will likely speed this up. Some users find acne on Trenbolone worse than when on any other steroid. Certainly Trenbolone is not recommended for female users due to its strong androgenic properties and the common side effects that manifest themselves in females who use strong androgen's.

Despite the fact that Trenbolone cannot aromatise, due to the progesterone route it can cause things like gynecomastia, but this will only really happen in the presence of estrogen. This does happen though in many users, as Trenbolone is usually stacked with a testosterone, which obviously can and will convert to estrogen. Gynecomastia from Trenbolone can be quite bad many will find, however if you do not suffer from this than other estrogenic side effects should not be of worry, as trenbolone does not cause any water retention or similar, but in fact often gives a hardened look and feel to the muscles.

Trenbolone also seems to give many users poor sleep patterns and insomnia. In addition, it can cause severe sweating in many, both during the night time and also just from doing the smallest of activities such as walking up stairs, etc. It also can impair to a certain degree, cardiovascular function, which means that it is not ideal for use in those who regular partake in such sports or activity that require a decent level of cardiovascular fitness.

Trenbolone also increases blood pressure in many users, some to such a degree that they have to cease using it. Thus it is recommended that one who wishes to use trenbolone, invests in a blood pressure monitor so they can regularly measure their blood pressure and keep an eye on it throughout the cycle.

Many people claim that Trenbolone has a negative effect on the kidneys. There are many of these claims certainly across the Internet since its use has become more widespread. However, there is no real evidence for these claims, and certainly I have seen many long-term users of Trenbolone have kidney function tests that are well within the normal range. Perhaps the reason for this theory is the fact that when using Trenbolone, many find that their urine can become a much darker more orange-brown colour. However, this is due to the fact that Trenbolone undergoes very little modification or breakdown and is excreted as a rust-coloured oxidised form in the urine. In addition to this, any damage to kidney may not even be directly due to the Trenbolone, but more to do with the increased sweating and water loss from excessive body heat whilst on Trenbolone, without the sufficient addition of water intake. Thus it is recommended if running Trenbolone to keep the water intake high.

As Trenbolone is such a strong steroid, it is very harsh on the HTPA axis and will shut down the body's natural testosterone production very easily and, for many, very harshly. It is comparable that people can experience with Deca, and longer cycles may need to include the use of HCG to restore one's own natural production of testosterone. Recovery from cycles containing Trenbolone is not easy, and requires a very well thought out and stringent PCT routine and diet.

For those who want more dramatic results and who are familiar with the use of Trenbolone cycles, then it is possible to use it at a higher dosage as long as it is tolerated. It is often used in overlapping cycles that look much like this one:

    Weeks One through Nine – Deca Durabolin and testosterone at recommended doses.
    Weeks 10, 11 and 12 – Add Trenbolone at 100mg/eod dose.
    Weeks 13 through 20 – Continue with testosterone, drop Deca Durabolin and adjust dose of Trenbolone as tolerated up to 100mg/ed.

Overall, Trenbolone is one of the most powerful and thereby most popular anabolic steroids available for use today.

Wednesday, February 4, 2015

Benefits of Testosterone Therapy

What can you expect from testosterone treatment? It's impossible to predict, because every man is different. Many men report improvement in energy level, sex drive, and quality of erections. Testosterone also increases bone density, muscle mass, and insulin sensitivity in some men.

Men also often report an improvement in mood from testosterone replacement. Whether these effects are barely noticeable, or a major boost, is highly individualized.
The common preparations of testosterone replacement have frequent, mild side effects. Testosterone side effects most often include rash, itching, or irritation at the site where the testosterone is applied.

Testosterone replacement so far seems to be generally safe. Experts emphasize that the benefits and risks of long-term testosterone therapy are unknown, because large clinical trials haven't yet been done.
Over time, the testicular “machinery” that makes testosterone gradually becomes less effective, and testosterone levels start to fall, by about 1% a year, beginning in the 40s. As men get into their 50s, 60s, and beyond, they may start to have signs and symptoms of low testosterone such as lower sex drive and sense of vitality, erectile dysfunction, decreased energy, reduced muscle mass and bone density, and anemia. Taken together, these signs and symptoms are often called hypogonadism (“hypo” meaning low functioning and “gonadism” referring to the testicles). Studies have shown that testosterone-replacement therapy may offer a wide range of benefits for men with hypogonadism, including improved libido, mood, cognition, muscle mass, bone density, and red blood cell production. But little consensus exists on what constitutes low testosterone, when testosterone supplementation makes sense, or what risks patients face. Much of the current debate focuses on the long-held belief that testosterone may stimulate prostate cancer.

The primary hallmark of low testosterone is low sexual desire or libido, but another can be erectile dysfunction, and any man who complains of erectile dysfunction should get his testosterone level checked. Men may experience other symptoms, such as more difficulty achieving an orgasm, less-intense orgasms, a smaller amount of fluid from ejaculation, and a feeling of numbness in the penis when they see or experience something that would normally be arousing. The more of these symptoms there are, the more likely it is that a man has low testosterone. Many physicians tend to dismiss these “soft symptoms” as a normal part of aging, but they are often treatable and reversible by normalizing testosterone levels. There are a number of drugs that may lessen sex drive, including the BPH drugs finasteride (Proscar) and dutasteride (Avodart). Those drugs can also decrease the amount of the ejaculatory fluid, no question. But a reduction in orgasm intensity usually does not go along with treatment for BPH. Erectile dysfunction does not usually go along with it either, though certainly if somebody has less sex drive or less interest, it’s more of a challenge to get a good erection.

How do you determine whether a man is a candidate for testosterone-replacement therapy:
There are two ways that we determine whether somebody has low testosterone. One is a blood test and the other is by characteristic symptoms and signs, and the correlation between those two methods is far from perfect. Generally men with the lowest testosterone have the most symptoms and men with highest testosterone have the least. But there are some men who have low levels of testosterone in their blood and have no symptoms.

Traditionally, anti-androgen medications have been used in combination with LHRH agonists to block testosterone. When anti-androgens are used alone it is called anti-androgen monotherapy. This approach is attractive for some men because it causes in a milder degree of testosterone blockade with less side effects. There are three anti-androgen agents - Casodex, Flutamide, and Nilutamide. They work by keeping testosterone away from the androgen receptor, an enzymatic "switch" inside the prostate cancer cell. This switch stimulates cell growth when it's turned on. Anti-androgens keep the switch in the "off" position. Because anti-androgens do not eliminate testosterone altogether, they have fewer side effects than the LHRH agonists such as Lupron, Trelstar, Eligard and Zoladex.

Clinicians with experience using Casodex monotherapy estimate that Casodex monotherapy is about 70% as effective as the LHRH agonists but with only 30% of the toxicity. Anti-androgens have been studied in prospective randomized trials as stand-alone therapy and combined with radiation. Overall, compared to LHRH agonists, side effects are certainly less. And compared to placebo, they clearly retard prostate cancer growth. The only caveat with Casodex monotherapy is a higher risk of breast growth. This can be partially or completely prevented with prophylactic breast radiation or an estrogen blocking pill called Femara.
Whenever the action of testosterone is inhibited, side effects ensue--hot flashes, osteoporosis, loss of muscle and loss of libido are typical. Many other side effects can also occur. Casodex monotherapy is less likely to induce muscle loss and less likely to reduce libido than the LHRH agonists. For example, only about 50% of younger men lose their libido whereas about 80% of men lose their libido with LHRH agonists.

There is one side effect that is more common with Casodex monotherapy than with LHRH agonists - breast enlargement. The medical term is gynecomastia. Gynecomastia occurs in 10% to 20% of men treated with LHRH agonists and in 50% to 60% of men on AAM. Gynecomastia can be prevented with radiation or an estrogen blocking pill called Femara. However, once breast tissue develops, it can only be removed with liposuction or surgery. To be effectively prevented, the radiation or the Femara must be started prior to starting treatment.

Thursday, January 29, 2015

Why bodybuilders prefer Sustanon 250?

Sustanon 250 is a testosterone compound comprised of four different ester based testosterone's. A common misconception among many steroid users is that Sustanon 250 carries with it more power than other testosterone forms, this is not so, it is merely testosterone, a powerful anabolic and androgenic hormone in its own right. Sustanon 250 is the trade name for a mixture or blend of 4 different variations of esterified Testosterone in a particular ratio. It typically contains: 30mg of Testosterone Propionate, 60mg of Testosterone Phenylpropionate, 60mg of Testosterone Isocaproate, and 100mg of Testosterone Decanoate for a total of 250mg worth of combined Testosterone esters (hence the number 250 in the name Sustanon 250). The idea in combining all of these different Testosterone esters is to provide a Testosterone drug that will provide the user with both a fast immediate release of Testosterone followed by a slower more extended release. The opposite of such a drug would be single forms of esterified Testosterone, such as a Testosterone Propionate product, which, of course, contains nothing but Testosterone Propionate in the vial. The greatest benefit of use is by far the ability to provide testosterone over an extended period of time but for the performance enhancer this proves to be of little use. When used for performance purposes the idea is not to simply provide testosterone but to do so and keep it at its peak level as well as stable. Due to this fact and since Sustanon-250 provides a dose that dwindles as time goes by for performance purposes it must be injected at minimum every three days with every other day being optimal.

Once you understand the manner in-which best suits your needs in-terms of injection frequency you can then enjoy the benefits of this powerful testosterone hormone. Like all testosterone's, regardless of the form, Sustanon-250 will greatly increase nitrogen retention in the muscles as well as protein synthesis; key factors in both growth and preservation.

Sustanon 250 is the brand name for the four part testosterone mixture originally created by Organon but as is common, as it was the first form of the compound the trade name Sustanon-250 is largely associated with all brands. Sust, as it is commonly known is comprised of only testosterone but it has four various esters attached; two short, one moderate and one long ester.

The composition of the compound is as follows:

    Testosterone Propionate: 30mg
    Testosterone Phenylpropionate: 60mg
    Testosterone Isocaproate: 60mg
    Testosterone Decanoate: 100mg

To understand Sustanon 250 we only need to understand testosterone and the manner in-which esters work. Once we understand the hormone testosterone and once we understand the esters attached are not hormones then we can understand how this particular steroidal compound is supposed to work.

The idea behind it was to provide a preparation of Testosterone that would have an advantage over single esterified Testosterone products in a medical and clinical setting. The idea here was also that of convenience, as Sustanon 250 requires more infrequent injections than does Testosterone Propionate or Testosterone Suspension, for example. What is interesting to note is that Sustanon 250 was never approved for use or sale in the United States, but Sustanon 250 remains a very popular drug on the international market. Sustanon 250 is most likely one of the most popular Testosterone preparations in use by bodybuilders and athletes. It was commonly thought that this was the case due to misconception that its more potent than single esterified forms of Testosterone, but this is not true. Esters attached to different anabolic steroids only affect the half-life and release time of whatever anabolic steroid they are bound to. In the case of Sustanon 250, there are four different esterified types of Testosterone to be considered – but Sustanon 250 is no more ‘potent’ of a Testosterone product than a straight Testosterone Enanthate preparation, for example.

The real true and primary reason for its popularity among athletes and bodybuilders is instead the amount of steroid one is getting for the money spent. A blend of four different esterified Testosterone variants is considered a great value for the money spent in comparison to the purchase of a single esterified Testosterone variant. However, over the years this price difference has not proven to be extremely advantageous over other forms of Testosterone. The sheer truth of the matter is that Sust 250 was not developed for athletes and bodybuilders, but instead with medical application in mind, and it is therefore an optimized product for those requiring medical treatment from it. The idea with this product was to provide patients with a far more convenient and comfortable dosing schedule where administration of the drug is concerned. Many patients prescribed it need only to worry about an injection every 3 – 4 weeks. As a bodybuilder or athlete, this is very unrealistic seeing as though athletes and bodybuilders would require injections of this product weekly, and blood plasma levels of Testosterone as a result would end up peaking to the same levels in the same amount of time that any other type of Testosterone product would end up doing. Therefore, the perceived benefits of Sustanon really do not apply to bodybuilders or athletes, or to individuals looking to use it for the purpose of performance/physique enhancement.

Sustanon 250, as previously mentioned is a precise blend of four different types of esterified Testosterone variants. Each of these Testosterone variants are molecules of Testosterone with esters chemically bonded to them at the 17th carbon position of the Testosterone structure (these esters are Propionate, Phenylpropionate, Isocaproate, and Decanoate). The addition of these esters slows down the rate of release of Testosterone into the bloodstream, which results in augmented half-lives of the different esterified forms of Testosterone. For example, Testosterone itself with no ester attached to it possesses a half-life of approximately 2 – 4 hours. When the Propionate ester is attached to it, for example, creating Testosterone Propionate, the half-life of Testosterone is now extended to 4.5 days, providing a slower release and activity of the hormone. Once in the body, enzymes work to cleave off and remove the attached ester from the Testosterone molecule, of which the end result is pure Testosterone free to do its job in the body. The process of enzymes removing the ester is what is responsible for the varying half-lives and release times of the different esterified variants.

Sustanon 250 itself with all of its Testosterone variants as a whole is designed to provide an initial fast peak of blood plasma Testosterone levels in approximately 24 – 48 hours following administration. After this, blood plasma levels of Testosterone are to remain elevated for a 21 day period due to the longer esterified Testosterone variants in the mix.

Cycles and Doses of Sustanone 250:
Sustanon-250 can be used for any cycle be it bulking or cutting and as most steroid users will build their cycles around testosterone Sust can be a fine choice. Testosterone is generally well-tolerated by healthy adult men who use it; as it is a hormone naturally found in our body it is not one we are unaccustomed to and in healthy adult men increased levels are often well received. Further, when stacking various anabolic androgenic steroids together, because our natural production of testosterone will cease it is important to keep some testosterone in the body for proper physical function and when you add in the beneficial anabolic characteristics it simply makes sense. Regardless of how you plan your cycles testosterone will in most cases necessarily be a part of them all and in many cases the only steroid you’ll ever need.

For the individual who uses Sustanon 250 as part of a testosterone replacement plan 250mg every 2-4 weeks is a common dose but this will be determined by your doctor. For the performance enhancer, as a general rule of thumb 500mg of testosterone is often considered the base dosing level and is perfect for any beginner. While this is a perfect beginners dose many will find it is all they ever need no matter how advanced they become. For the hardcore, doses of 1,000mg per week are fairly common place and even beyond in bodybuilding circles, particularly those who fall in the realm of competition. Understand, when the dose increases, while the rewards may as well so do the risks associated.

Many will find 12-16 week cycles of Sustanon 250 to be perfect and very well-tolerated in most cases, however, a solid post cycle therapy (PCT) plan is necessary once discontinued. Because Sustanon-250 carries long esters you will necessarily begin PCT 3 weeks after your final Sust administration which may include hCG, Nolva and/or Clomid. Those who use hCG are advised to begin use approximately ten days before Nolva/Comid for approximately ten days of use.