Lowering the level of plasma binding proteins is also not the only mechanism that allows for an increased level of free testosterone. Steroids that display a high affinity for these proteins may also increase the level of free testosterone by competing with it for binding. Obviously if testosterone finds it more difficult to locate available plasma proteins in the presence of the additional compound, more will be left in an unbound state. A number of steroids including dihydrotestosterone, Proviron and Oral-Turinabol, (chlorodehydromethyltestosterone) display a strong tendency for this effect. If the level of free-testosteron can be altered by the use of different anabolic/androgeniс steroids, the possibility also exists that one steroid car increase the potency of another through these same mechanisms. For example, Proviron is a poor anaboliq but its extremely high affinity for SHBG might make is useful by allowing the displacement of other steroids thai are more active in these tissues. We must not let this discussion lead us into thinking than binding proteins serve no valuable function.
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